Diuretic Potency of Belalai Gajah Plants (Clinacanthus nutans (Burm.fil.) Lindau)

نویسندگان

چکیده

Backgrounds: The use of belalai gajah plants (Clinacanthus nutans (Burm.fil.) Lindau) is believed by the Chinese community to be able treat hypertension, so prove whether this power exists in do a diuretic activity test. Objective Study: determine presence potency plants. Methods: This test used male white rats Sprague Dawley strain with body weight 200-250 grams aged 2-2.5 months as many 35 which were divided into 7 groups. first group or no treatment, second 2.8 ml/200 g distilled water, third and fourth groups 0.72 mg/200 furosemide 1.44 weight, fifth, sixth, seventh administration extract doses 75 mg/kg 150 300 weight. uses Cumming method. Urine collection was carried out for 24 hours, then urine volume, pH, also sodium potassium levels rat measured. Results: results study showed that without water at dose resulted volume 13.01 ± 0.07 ml; 13.77±0.17 15.78± 0.39 18.13±0.23 14.05±0.06 16.78±0.12 17.98±0.09 ml (p<0.5). Furthermore, pH successively 7.02 0.04; 7.11±0.02; 7.21±0.02; 7.58±0.18; 7.15±0.03; 7.37±0.03; 7.44±0.02 (p>0.5). respectively 1.06±0.03 mEq/ 1.14±0.03 mEq/ml; 2.17±0.09 4.01±0.069 1.34±0.08 1.49±0.02mEq/ml; 1.77 ±0.05 mEq/ml (p<0.5) urinary 0.5±0.03 mEq/ml, respectively; 0.57±0.018 0.98±0.023 1.88±0.04 0.6±0.02 0.76±0.021 0.87±0.032 Conclusion: Belalai has ability increase close administering had mg furosemide/200 Giving are water.

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ژورنال

عنوان ژورنال: Pharmacognosy Journal

سال: 2023

ISSN: ['0975-3575']

DOI: https://doi.org/10.5530/pj.2023.15.56